IL34 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/6/66/4dkc.png/250px-4dkc.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4DKC, 4DKD, 4DKE, 4DKF |
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Identifiers |
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Aliases | IL34, C16orf77, IL-34, Interleukin 34 |
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External IDs | OMIM: 612081; MGI: 1923777; HomoloGene: 12648; GeneCards: IL34; OMA:IL34 - orthologs |
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Gene location (Human) |
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![Chromosome 16 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Ideogram_human_chromosome_16.svg/300px-Ideogram_human_chromosome_16.svg.png) | Chr. | Chromosome 16 (human)[1] |
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| Band | 16q22.1 | Start | 70,579,895 bp[1] |
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End | 70,660,682 bp[1] |
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Gene location (Mouse) |
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![Chromosome 8 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Ideogram_house_mouse_chromosome_8.svg/260px-Ideogram_house_mouse_chromosome_8.svg.png) | Chr. | Chromosome 8 (mouse)[2] |
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| Band | 8|8 E1 | Start | 111,468,461 bp[2] |
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End | 111,532,556 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - tibial nerve
- skin of arm
- spleen
- skin of abdomen
- skin of leg
- sural nerve
- parotid gland
- vena cava
- buccal mucosa cell
- Skeletal muscle tissue of rectus abdominis
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| Top expressed in | - superior frontal gyrus
- dentate gyrus of hippocampal formation granule cell
- zygote
- primary visual cortex
- right kidney
- lip
- secondary oocyte
- muscle of thigh
- proximal tubule
- embryo
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - macrophage colony-stimulating factor receptor binding
- cytokine activity
- growth factor activity
- protein binding
- identical protein binding
| Cellular component | - extracellular region
- extracellular space
| Biological process | - positive regulation of monocyte differentiation
- positive regulation of macrophage differentiation
- positive regulation of protein phosphorylation
- innate immune response
- inflammatory response
- positive regulation of cell population proliferation
- immune system process
- regulation of signaling receptor activity
- cytokine-mediated signaling pathway
- microglial cell proliferation
- positive regulation of gene expression
- positive regulation of oligodendrocyte differentiation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001172771 NM_001172772 NM_152456 |
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RefSeq (protein) | |
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NP_001166242 NP_001166243 NP_689669 |
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Location (UCSC) | Chr 16: 70.58 – 70.66 Mb | Chr 8: 111.47 – 111.53 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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