Ketoheksokinaza
| Ketoheksokinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Ketoheksokinaza homodimer, Human | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.1.3 | ||||||||
| CAS broj | 9030-50-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ketoheksokinaza (EC 2.7.1.3, ketoheksokinaza (fosforilacija)) je enzim sa sistematskim imenom ATP:D-fruktoza 1-fosfotransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + D-fruktoza ADP + D-fruktoza 1-fosfat
D-sorboza, D-tagatoza, 5-dezhidro-D-fruktoza i brojne druge ketoze i njihovi analozi takođe mogu da bufu supstrati.
Reference
- ↑ Cori, G.T., Ochoa, S., Slein, M.W. and Cori, C.F. (1951). „The metabolism of fructose in liver. Isolation of fructose-1-phosphate and inorganic pyrophosphate”. Biochim. Biophys. Acta 7: 304-317. PMID 14858418.
- ↑ Hers, H.G. (1952). „La fructokinase du foie”. Biochim. Biophys. Acta 8: 416-423. PMID 13208667.
- ↑ Parks, R.E., Ben-Gershom, E. and Lardy, H.A. (1957). „Liver fructokinase”. J. Biol. Chem. 227: 231-242. PMID 13449068.
- ↑ Raushel, F.M. and Cleland, W.W. (1977). „Bovine liver fructokinase: purification and kinetic properties”. Biochemistry 16: 2169-2175. PMID 193556.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Ketohexokinase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
