Acetil-KoA C-aciltransferaza
| Acetil-KoA C-aciltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.16 | ||||||||
| CAS broj | 9029-97-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Acetil-KoA C-aciltransferaza (EC 2.3.1.16, beta-ketotiolaza, 3-ketoacil-KoA tiolaza, KAT, beta-ketoacil koenzim A tiolaza, beta-ketoacil-KoA tiolaza, beta-ketoadipil koenzim A tiolaza, beta-ketoadipil-KoA tiolaza, 3-ketoacil KoA tiolaza, 3-ketoacil koenzim A tiolaza, 3-ketoacilna tiolaza, 3-ketotiolaza, 3-oksoacil-KoA tiolaza, 3-oksoacil-koenzim A tiolaza, 6-oksoacil-KoA tiolaza, acetoacetil-KoA beta-ketotiolaza, acetil-KoA aciltransferaza, ketoacil-KoA aciltransferaza, ketoacil-koenzim A tiolaza, dugolančana 3-oksoacil-KoA tiolaza, oksoacil-koenzim A tiolaza, pro-3-ketoacil-KoA tiolaza, tiolaza I, 2-metilacetoacetil-KoA tiolaza) je enzim sa sistematskim imenom acil-KoA:acetil-KoA C-aciltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acil-KoA + acetil-KoA KoA + 3-oksoacil-KoA
Reference
- ↑ Beinert, H., Bock, R.M., Goldman, D.S., Green, D.E., Mahler, H.R., Mii, S., Stansly, P.G. and Wakil, S.J. (1953). „A synthesis of dl-cortisone acetate”. J. Am. Chem. Soc. 75: 4111-4112.
- ↑ Goldman, D.S. (1954). „Studies on the fatty acid oxidizing system of animal tissue. VII. The β-ketoacyl coenzyme A cleavage enzyme”. J. Biol. Chem. 208: 345-357. PMID 13174544.
- ↑ Stern, J.R., Coon, M.J. and del Campillo, A. (1953). „Enzymatic breakdown and synthesis of acetoacetate”. Nature 171: 28-30. PMID 13025466.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Vanjske veze
- MeSH Acetyl-CoA+C-acyltransferase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
