Tritoqualine
Chemical compound
- R06AX21 (WHO)
- 7-amino-4,5,6-triethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one
- 14504-73-5
- 72145
- 65119
- F4MW5166YH
- DTXSID10864514
- Interactive image
- CCOC1=C(C(=C(C2=C1C(OC2=O)C3C4=C(C5=C(C=C4CCN3C)OCO5)OC)N)OCC)OCC
Tritoqualine, also known as hypostamine, is an inhibitor of the enzyme histidine decarboxylase and therefore an atypical antihistamine, used for the treatment of urticaria and allergic rhinitis[1] with no known adverse effects.[citation needed]
References
- ^ Pradalier A, Hentschel V, Prouzeau S, Legallais D, Lefrancois G (April 2003). "Randomized, placebo controlled study of tritoqualine (hypostamine*) in the treatment of perennial allergic rhinitis". Revue Française d'Allergologie et d'Immunologie Clinique. 43 (3): 175–9. doi:10.1016/S0335-7457(03)00047-9.
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Antihistamines (R06)
- Diarylmethoxyalkylamines: Bromazine (bromodiphenhydramine)
- Carbinoxamine
- Chlorphenoxamine
- Clemastine
- Diphenhydramine (+naproxen)
- Diphenylpyraline
- Doxylamine
- Ebastine
- Orphenadrine
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- Etodroxizine
- Hydroxyzine
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- Oxatomide
- Phenylpyridinylpropanamines: Brompheniramine
- Chlorphenamine
- Dexbrompheniramine (+pseudoephedrine)
- Dexchlorpheniramine (+betamethasone)
- Pheniramine
- Phenylpiperazines: Antidepressants (e.g., trazodone)
- Phenbenzamine
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