Protein-coding gene in the species Homo sapiens
| TMSB15B |
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| Identifiers |
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| Aliases | TMSB15B, Tbeta15b, thymosin beta 15B, TMSNB, TMSB15A, TMSL8 |
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| External IDs | OMIM: 301011; GeneCards: TMSB15B; OMA:TMSB15B - orthologs |
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| Gene ontology |
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| Molecular function | - actin binding
- actin monomer binding
- molecular function
- DNA-binding transcription factor activity, RNA polymerase II-specific
| | Cellular component | - cytoskeleton
- cytoplasm
- cellular component
| | Biological process | - actin filament organization
- regulation of cell migration
- sequestering of actin monomers
- positive regulation of cell migration
- regulation of transcription by RNA polymerase II
| | Sources:Amigo / QuickGO |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | |
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NM_001350211
NM_001350212
NM_001350213
NM_194324 |
| |
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| RefSeq (protein) | NP_001337140
NP_001337141
NP_001337142
NP_919305
NP_068832
|
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NP_068832 |
| |
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| Location (UCSC) | n/a | n/a |
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| PubMed search | [1] | n/a |
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| Wikidata |
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Thymosin beta-15B is a protein that, in humans, is encoded by the TMSB15B gene. The protein is identical in aminoacid sequence to Thymosin beta-15A, product of the TMSB15A gene, although synthesis of the two proteins is independently regulated.[2][3]
See also
References
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: thymosin beta 15B".
- ^ Banyard J, Hutchinson LM, Zetter BR (September 2007). "Thymosin beta-NB is the human isoform of rat thymosin beta15". Ann. N. Y. Acad. Sci. 1112 (1): 286–96. Bibcode:2007NYASA1112..286B. doi:10.1196/annals.1415.024. PMID 17567946. S2CID 41879096.
Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Banyard J, Barrows C, Zetter BR (2009). "Differential regulation of human thymosin beta 15 isoforms by transforming growth factor beta 1". Genes Chromosomes Cancer. 48 (6): 502–9. doi:10.1002/gcc.20659. PMC 2756613. PMID 19296525.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
