AHCTF1

Protein-coding gene in the species Homo sapiens
AHCTF1
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

4I0O

Identifiers
AliasesAHCTF1, ELYS, MST108, TMBS62, MSTP108, AT-hook containing transcription factor 1
External IDsOMIM: 610853; MGI: 1915033; HomoloGene: 9142; GeneCards: AHCTF1; OMA:AHCTF1 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for AHCTF1
Genomic location for AHCTF1
Band1q44Start246,839,098 bp[1]
End246,931,948 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for AHCTF1
Genomic location for AHCTF1
Band1 H4|1 83.62 cMStart179,572,459 bp[2]
End179,631,245 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • endothelial cell

  • Achilles tendon

  • secondary oocyte

  • sperm

  • ventricular zone

  • Brodmann area 23

  • testicle

  • internal globus pallidus

  • left testis

  • middle temporal gyrus
Top expressed in
  • tail of embryo

  • spermatocyte

  • spermatid

  • genital tubercle

  • epiblast

  • seminiferous tubule

  • zygote

  • secondary oocyte

  • otic placode

  • otic vesicle
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • DNA binding
  • DNA-binding transcription factor activity
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • cytoplasm
  • cytosol
  • nuclear membrane
  • nuclear periphery
  • nuclear matrix
  • nuclear pore
  • nucleoplasm
  • chromosome
  • nuclear pore outer ring
  • chromatin
  • extracellular exosome
  • chromosome, centromeric region
  • nucleus
  • kinetochore
  • nuclear envelope
Biological process
  • mRNA transport
  • nuclear pore complex assembly
  • regulation of transcription, DNA-templated
  • cytokinesis
  • cell division
  • protein transport
  • cell cycle
  • sister chromatid cohesion
  • transport
  • regulation of transcription by RNA polymerase II
  • regulation of cytokinesis
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

25909

226747

Ensembl

ENSG00000153207

ENSMUSG00000026491

UniProt

Q8WYP5

Q8CJF7

RefSeq (mRNA)

NM_015446
NM_001323342
NM_001323343
NM_175865

NM_026375

RefSeq (protein)

NP_001310271
NP_001310272
NP_056261

NP_080651

Location (UCSC)Chr 1: 246.84 – 246.93 MbChr 1: 179.57 – 179.63 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein ELYS is a protein that in humans is encoded by the AHCTF1 gene.[5][6]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000153207 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026491 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kimura N, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Natori O, Nobuhisa I, Taga T (Apr 2002). "Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues". Genes Cells. 7 (4): 435–46. doi:10.1046/j.1365-2443.2002.00529.x. PMID 11952839. S2CID 22977237.
  6. ^ "Entrez Gene: AHCTF1 AT hook containing transcription factor 1".

External links

Further reading

  • Rasala BA, Orjalo AV, Shen Z, et al. (2007). "ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division". Proc. Natl. Acad. Sci. U.S.A. 103 (47): 17801–6. doi:10.1073/pnas.0608484103. PMC 1635652. PMID 17098863.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
  • Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.


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